FORMULATION OF CONTROLLED RELEASE MATRIX TABLET OF DICLOFENAC SODIUM USING CROSS LINKED STARCH UREA

Formulation of Controlled Release Matrix Tablet of Diclofenac Sodium Using Cross Linked Starch Urea

The présent works aims to develop controlled release matrix tablet of diclofenac sodium with modified starch cross linked starch urea as an sustained release polymer and to evaluate the prepared dosage form for physical parameters like weight variation, hardness, friability and drug content. Cross linked starch urea is modified starch introducing desirable alterations in the starch structure so...

Formulation of Controlled Release Pelubiprofen Tablet Using Matrix-Forming Polymers

Preparation and Evaluation of Sustained Release Matrix Tablet of Diclofenac Sodium using Natural Polymer

Sustained release tablets of Diclofenac Sodium were fabricated using Cashew nut tree gum, HPMC and Carbopol . The tablets were evaluated for preformulation studies like angle of repose, bluk density, compressibility index and physical characteristics like hardness, weight variation, fraibilty and drug content. In-vitro release of drug was performed in PBS pH 7.2 for twelve hours. All the physic...

Diclofenac Sodium Loaded Sustained Release Matrix Tablet Possessing Natural and Synthetic Polymers: Formulation and in vitro Characterization

Object: The objective of the present study was to investigate the effect of various concentrations of natural and synthetic polymers on in vitro drug release from sustained release matrix tablets. Materials and method: HPMC K4M and acacia gum were used as synthetic (hydrophilic) and natural (hydrophobic) polymers respectively. Diclofenac sodium was used as a model drug to study the in vitro rel...

Development and Evaluation of Extended Release Ethylcellulose Based Matrix Tablet of Diclofenac Sodium

Objective: The present study involved the preparation of Diclofenac sodium extended release hydrophobic matrix tablets formulated from Ethylcellulose polymer following its different grades, Ethocel Standard Premium and Ethocel Standard FP Premium. Methods: The matrix tablets were prepared with wet granulation method. Lubricated blends were characterized for physical properties like loose bulk d...